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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIPK2 All Species: 26.67
Human Site: S168 Identified Species: 65.19
UniProt: O43353 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43353 NP_003812.1 540 61195 S168 K I A D F G L S K W R M M S L
Chimpanzee Pan troglodytes XP_519850 539 61066 S168 K I A D F G L S K W R M M S L
Rhesus Macaque Macaca mulatta XP_001084563 540 61225 S168 K I A D F G L S K W R M M S L
Dog Lupus familis XP_535125 538 61029 S168 K I A D F G L S K W R T M S L
Cat Felis silvestris
Mouse Mus musculus P58801 539 60382 S168 K I A D F G L S K W R M M S L
Rat Rattus norvegicus Q9Z2P5 478 52215 L118 C P R P W P L L C R L L E E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511321 791 87316 F163 Y H V K I S D F G L A K C S G
Chicken Gallus gallus NP_001026114 574 63953 S173 K I A D F G M S K W R V I S M
Frog Xenopus laevis NP_001080415 720 79835 D162 H Y H V K I S D F G L A K W N
Zebra Danio Brachydanio rerio NP_919392 584 65933 S178 K I A D F G L S K W R Q L S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.4 86.6 N.A. 84.2 24.8 N.A. 25.6 63.4 25.9 49.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 97.7 90.7 N.A. 89.8 40.9 N.A. 39.7 74.2 44.3 64.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 6.6 N.A. 6.6 73.3 0 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 26.6 N.A. 6.6 100 0 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 70 0 0 0 0 0 0 0 10 10 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % C
% Asp: 0 0 0 70 0 0 10 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 70 0 0 10 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 70 0 0 10 10 0 0 0 0 10 % G
% His: 10 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 70 0 0 10 10 0 0 0 0 0 0 10 0 10 % I
% Lys: 70 0 0 10 10 0 0 0 70 0 0 10 10 0 0 % K
% Leu: 0 0 0 0 0 0 70 10 0 10 20 10 10 0 50 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 40 50 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 10 70 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 10 70 0 0 0 0 0 80 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 10 10 0 0 0 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 10 0 0 0 0 70 0 0 0 10 0 % W
% Tyr: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _